Which statement correctly differentiates tolerance, dependence, and withdrawal?

Which statement correctly differentiates tolerance, dependence, and withdrawal?

• A. Tolerance is a reduced response requiring higher doses; dependence is a physiological adaptation with withdrawal symptoms when use stops; withdrawal includes tremors, anxiety, and autonomic changes when intake is reduced or stopped.
• B. Tolerance means increased sensitivity; dependence means no withdrawal; withdrawal is a craving only.
• C. Tolerance means withdrawal occurs quickly; dependence means you can't stop; withdrawal is purely psychological.
• D. Tolerance is a physiological need to drink more to avoid headaches; dependence is a state of craving with no physical symptoms.

Answer: (A)